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SAE1 Recombinant Protein (Human)

CAT: 0247-OPED00134-25UGSize: 25 µgDry Ice: NoHazardous: No
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CAT#:0247-OPED00134-25UGSize:25 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9000-83-3
Gene Name
SUMO1 activating enzyme subunit 1|ubiquitin like modifier activating enzyme 2
Gene Aliases
Activator of SUMO1; anthracycline-associated resistance ARX; AOS1; ARX; HRIHFB2115; HSPC140; SAE2; sentrin/SUMO-activating protein AOS1; SUA1; SUMO-1 activating enzyme E1 N subunit; SUMO-1 activating enzyme subunit 1; SUMO1 activating enzyme subunit 2; SUMO-1 activating enzyme subunit 2; SUMO-activating enzyme subunit 1; SUMO-activating enzyme subunit 2; UBA2, ubiquitin-activating enzyme E1 homolog; ubiquitin-like 1-activating enzyme E1A; ubiquitin-like 1-activating enzyme E1B; Ubiquitin-like modifier-activating enzyme 2; ubiquitin-like protein SUMO-1 activating enzyme; UBLE1A.
Gene ID
10054|10055
Accession Number
NP_001014188.1
Reactivity
Homo sapiens|Human
Target
The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.
Type
Protein
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid. In HEPES, pH 8.0, containing 110mM potassium acetate, 2mM magnesium acetate, 0.5mM EGTA and 1mM DTT.
Reconstitution
Store at -80C
Molecular Weight
38 kDa, 90 kDa
Protein Length
Recombinant
NCBI Gene Symbol
SAE1|UBA2
Host or Source
E. Coli
Protein Name
SUMO-activating enzyme subunit 1|SUMO-activating enzyme subunit 2
Gene Name URL
SAE1|UBA2
Nucleotide Accession Number
NM_001014166.1

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