SERPINE1 Recombinant Protein
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SERPINE1 Recombinant Protein
Gene Aliases:
Endothelial plasminogen activator inhibitor; Serpin E1.Reactivity:
Mouse|Mus musculusTarget:
Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU) . As PLAT inhibitor, it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots. As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading. Acts as a regulator of cell migration, independently of its role as protease inhibitor. It is required for stimulation of keratinocyte migration during cutaneous injury repair (By similarity) . Involved in cellular and replicative senescence (PubMed:16862142) . Plays a role in alveolar type 2 cells senescence in the lung (PubMed:28722352) . Is involved in the regulation of cementogenic differentiation of periodontal ligament stem cells, and regulates odontoblast differentiation and dentin formation during odontogenesis (By similarity) .Conjugation:
UnconjugatedType:
ProteinSource:
E.coliApplications:
Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blotAssay Protocol:
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) ProtocolConcentration:
200 ug/mL (prior to lyoph)Format:
Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.Reconstitution:
2°C to 8°C|-80°CMolecular Weight:
28kDaProtein Length:
RecombinantNCBI Gene Symbol:
SERPINE1Host or Source:
E.coliProtein Name:
Plasminogen activator inhibitor 1Gene Name URL:
SERPINE1CAS Number:
9000-83-3
