Products for Research Use Only
RegisterLogin

LCN2 Recombinant Protein

CAT: 0247-OPCD05661-50UGSize: 50 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0247-OPCD05661-50UGSize:50 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
9000-83-3
Gene Name
Lipocalin 2
Gene Aliases
24p3;25 kDa alpha-2-microglobulin-related subunit of MMP-9; Lipocalin-2; migration-stimulating factor inhibitor; MSFI; neutrophil gelatinase-associated lipocalin; NGAL; oncogene 24p3; p25; siderocalin LCN2.
Gene ID
3934
Accession Number
NP_005555.2
Reactivity
Homo sapiens|Human
Target
Iron-trafficking protein involved in multiple processes such as apoptosis, innate immunity and renal development. Binds iron through association with 2,5-dihydroxybenzoic acid (2,5-DHBA), a siderophore that shares structural similarities with bacterial enterobactin, and delivers or removes iron from the cell, depending on the context. Iron-bound form (holo-24p3) is internalized following binding to the SLC22A17 (24p3R) receptor, leading to release of iron and subsequent increase of intracellular iron concentration. In contrast, association of the iron-free form (apo-24p3) with the SLC22A17 (24p3R) receptor is followed by association with an intracellular siderophore, iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration. Involved in apoptosis due to interleukin-3 (IL3) deprivation: iron-loaded form increases intracellular iron concentration without promoting apoptosis, while iron-free form decreases intracellular iron levels, inducing expression of the proapoptotic protein BCL2L11/BIM, resulting in apoptosis. Involved in innate immunity, possibly by sequestrating iron, leading to limit bacterial growth.
Conjugation
Unconjugated
Type
Protein
Source
E.coli
Applications
Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
200 ug/mL (prior to lyoph)
Format
Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Reconstitution
2°C to 8°C|-80°C
Molecular Weight
24kDa
Protein Length
Recombinant
NCBI Gene Symbol
LCN2
Host or Source
E.coli
Protein Name
Neutrophil gelatinase-associated lipocalin
Gene Name URL
LCN2
Nucleotide Accession Number
NM_005564.4

Related Products

CatalogName
OPPA00818-2UGLCN2 Protein
OCOA12550-20UGLCN2 Protein Lysate
OAAN03276-100ULLCN2 Antibody
OACD00299-200ULLCN2 Antibody
OACD05972-100ULLCN2 Antibody
OAAN03276-50ULLCN2 Antibody
OACD05971-1MLLCN2 Antibody
OACD00299-1MLLCN2 Antibody
OACD00299-100ULLCN2 Antibody
OOPA00081-20UGLCN2 Antibody

Alternative Products

CatalogName
32-2498-10LCN2 Recombinant Protein
ARP2783-01Recombinant Mouse Lcn2 Protein
ARP2781-01Recombinant Human LCN2 Protein
PPT-16621Mouse LCN2 Recombinant Protein
RP067950LCN2 Recombinant Protein (Human)
RP147065LCN2 Recombinant Protein (Mouse)
RP207914LCN2 Recombinant Protein (Rat)
ARP2782-01Recombinant Rat Lcn2 Protein
32-2500-20LCN2 Pichia Recombinant Protein
PPT-13637Human LCN2 Recombinant Protein

Popular Products