C2CD3 Recombinant Protein

CAT: 0247-OPCD01752-200UGSize: 200 µgDry Ice: NoHazardous: No
CAT#:0247-OPCD01752-200UGSize:200 µg
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CAS Number
9000-83-3
Gene Name
C2 domain containing 3 centriole elongation regulator
Gene Aliases
C2 calcium dependent domain containing 3; C2 domain-containing protein 3; OFD14.
Gene ID
26005
Accession Number
NP_001273506.1
Reactivity
Homo sapiens|Human
Target
Component of the centrioles that acts as a positive regulator of centriole elongation (PubMed:24997988) . Promotes assembly of centriolar distal appendage, a structure at the distal end of the mother centriole that acts as an anchor of the cilium, and is required for recruitment of centriolar distal appendages proteins CEP83, SCLT1, CEP89, FBF1 and CEP164. Not required for centriolar satellite integrity or RAB8 activation. Required for primary cilium formation (PubMed:23769972) . Required for sonic hedgehog/SHH signaling and for proteolytic processing of GLI3.
Conjugation
Unconjugated
Type
Protein
Source
E.coli
Applications
Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
200 ug/mL (prior to lyoph)
Format
Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Reconstitution
2°C to 8°C|-80°C
Molecular Weight
54kDa
Protein Length
Recombinant
NCBI Gene Symbol
C2CD3
Host or Source
E.coli
Protein Name
C2 domain-containing protein 3
Gene Name URL
C2CD3
Nucleotide Accession Number
NM_001286577.1

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