C2CD3 Antibody

CAT: 0247-OACD02064-1MLSize: 1 mLDry Ice: NoHazardous: No
CAT#:0247-OACD02064-1MLSize:1 mL
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CAS Number
9007-83-4
Gene Name
C2 domain containing 3 centriole elongation regulator
Gene Aliases
C2 calcium dependent domain containing 3; C2 domain-containing protein 3; OFD14.
Gene ID
26005
Accession Number
NP_001273506.1
Reactivity
Human
Immunogen
Range: Asn1432 - Leu1647
Target
Component of the centrioles that acts as a positive regulator of centriole elongation (PubMed:24997988) . Promotes assembly of centriolar distal appendage, a structure at the distal end of the mother centriole that acts as an anchor of the cilium, and is required for recruitment of centriolar distal appendages proteins CEP83, SCLT1, CEP89, FBF1 and CEP164. Not required for centriolar satellite integrity or RAB8 activation. Required for primary cilium formation (PubMed:23769972) . Required for sonic hedgehog/SHH signaling and for proteolytic processing of GLI3.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot
Purification
Affinity Purified; Protein A Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Format
Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Reconstitution
2°C to 8°C|-20°C
Molecular Weight
210 kDa
Fragment
IgG
Specificity
The antibody is a rabbit polyclonal antibody raised against C2CD3. It has been selected for its ability to recognize C2CD3 in immunohistochemical staining and western blotting.
NCBI Gene Symbol
C2CD3
Host or Source
Rabbit
Protein Name
C2 domain-containing protein 3
Gene Name URL
C2CD3
Nucleotide Accession Number
NM_001286577

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