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APLN Recombinant Protein

CAT: 0247-OPCD01393-200UGSize: 200 µgDry Ice: NoHazardous: No
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CAT#:0247-OPCD01393-200UGSize:200 µg
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CAS Number
9000-83-3
Gene Name
Apelin
Gene Aliases
6030430G11Rik; Apel; apelin; APJ endogenous ligand; preproapelin.
Gene ID
30878
Accession Number
NP_038940.1
Reactivity
Mouse|Mus musculus
Target
Endogenous ligand for the apelin receptor (APLNR) . Drives internalization of APLNR (By similarity) . Apelin-36 dissociates more hardly than (pyroglu) apelin-13 from APLNR (By similarity) . Hormone involved in the regulation of cardiac precursor cell movements during gastrulation and heart morphogenesis (By similarity) . Has an inhibitory effect on cytokine production in response to T-cell receptor/CD3 cross-linking; the oral intake of apelin in the colostrum and the milk might therefore modulate immune responses in neonates (PubMed:10525157) . Plays a role in early coronary blood vessels formation (PubMed:28890073) . Mediates myocardial contractility in an ERK1/2-dependent manner (By similarity) . May also have a role in the central control of body fluid homeostasis by influencing vasopressin release and drinking behavior (PubMed:11359874) .
Conjugation
Unconjugated
Type
Protein
Source
E.coli
Applications
Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
200 ug/mL (prior to lyoph)
Format
Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Reconstitution
2°C to 8°C|-80°C
Molecular Weight
39kDa
Protein Length
Recombinant
NCBI Gene Symbol
Apln
Host or Source
E.coli
Protein Name
Apelin
Gene Name URL
Apln
Nucleotide Accession Number
NM_013912.4

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