APLN Antibody

• Gene Name:

  Apelin

• Gene Aliases:

  6030430G11Rik; Apel; apelin; APJ endogenous ligand; preproapelin.

• Gene ID:

  30878

• Accession Number:

  NP_038940.1

• Reactivity:

  Mouse

• Immunogen:

  Range: Val23 - Phe77

• Target:

  Endogenous ligand for the apelin receptor (APLNR) . Drives internalization of APLNR (By similarity) . Apelin-36 dissociates more hardly than (pyroglu) apelin-13 from APLNR (By similarity) . Hormone involved in the regulation of cardiac precursor cell movements during gastrulation and heart morphogenesis (By similarity) . Has an inhibitory effect on cytokine production in response to T-cell receptor/CD3 cross-linking; the oral intake of apelin in the colostrum and the milk might therefore modulate immune responses in neonates (PubMed:10525157) . Plays a role in early coronary blood vessels formation (PubMed:28890073) . Mediates myocardial contractility in an ERK1/2-dependent manner (By similarity) . May also have a role in the central control of body fluid homeostasis by influencing vasopressin release and drinking behavior (PubMed:11359874) .

• Clonality:

  Polyclonal

• Type:

  Polyclonal Antibody

• Applications:

  Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot

• Purification:

  Affinity Purified; Protein A Purified

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  0.3 mg/ml

• Format:

  Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

• Reconstitution:

  2°C to 8°C|-20°C

• Molecular Weight:

  9 kDa

• Fragment:

  IgG

• Specificity:

  The antibody is a rabbit polyclonal antibody raised against APLN. It has been selected for its ability to recognize APLN in immunohistochemical staining and western blotting.

• NCBI Gene Symbol:

  Apln

• Host or Source:

  Rabbit

• Protein Name:

  Apelin

• Gene Name URL:

  Apln

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_013912