Products for Research Use Only
RegisterLogin

AGER Recombinant Protein

CAT: 0247-OPCD01183-50UGSize: 50 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0247-OPCD01183-50UGSize:50 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
9000-83-3
Gene Aliases
Receptor for advanced glycosylation end products.
Reactivity
Rat|Rattus norvegicus
Target
Mediates interactions of advanced glycosylation end products (AGE) . These are nonenzymatically glycosylated proteins which accumulate in vascular tissue in aging and at an accelerated rate in diabetes. Acts as a mediator of both acute and chronic vascular inflammation in conditions such as atherosclerosis and in particular as a complication of diabetes. AGE/RAGE signaling plays an important role in regulating the production/expression of TNF-alpha, oxidative stress, and endothelial dysfunction in type 2 diabetes. Interaction with S100A12 on endothelium, mononuclear phagocytes, and lymphocytes triggers cellular activation, with generation of key proinflammatory mediators. Receptor for amyloid beta peptide. Contributes to the translocation of amyloid-beta peptide (ABPP) across the cell membrane from the extracellular to the intracellular space in cortical neurons. ABPP-initiated RAGE signaling, especially stimulation of p38 mitogen-activated protein kinase (MAPK), has the capacity to drive a transport system delivering ABPP as a complex with RAGE to the intraneuronal space. Can also bind oligonucleotides (By similarity) . Interaction with S100B after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling.
Conjugation
Unconjugated
Type
Protein
Source
E.coli
Applications
Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
200 ug/mL (prior to lyoph)
Format
Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Reconstitution
2°C to 8°C|-80°C
Molecular Weight
19kDa
Protein Length
Recombinant
NCBI Gene Symbol
AGER
Host or Source
E.coli
Protein Name
Advanced glycosylation end product-specific receptor
Gene Name URL
AGER

Related Products

CatalogName
OCOA05234-20UGAGER Protein Lysate
OCOA00406-20UGAGER Protein Lysate
OAAJ02854-100ULAGER Antibody
OAAJ06879-100ULAGER Antibody
OABB00167-100UGAGER Antibody
AAP41642-100UGAGER Peptide (AAP41642)
AAP41643-100UGAGER Peptide (AAP41643)
OASG06252-100ULAGER Antibody - middle region
OABF00086-100ULAGER Antibody (OABF00086-100UL)
OKCD06622-96WAGER ELISA Kit (Human)

Alternative Products

CatalogName
91-379AGER Recombinant Protein
MBS8248516-01Recombinant Human AGER Protein
NBP2-57198PEPAGER Recombinant Protein Antigen
RP000712AGER Recombinant Protein (Human)
RP114764AGER Recombinant Protein (Mouse)
RP189503AGER Recombinant Protein (Rat)
ARP7270-01Recombinant Human AGER / RAGE Protein
ATGP3923-020Recombinant human RAGE/AGER protein
E51P90084AGER protein, Human, Recombinant (His)
PPT-14914Human RAGE/AGER Recombinant Protein

Popular Products