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Galectin 9 Antibody

CAT: 0013-GTR18610096Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR18610096Size:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Galectin 9 Antibody
Product Name Alternative
Galectin-9; Gal-9; LGALS9; Ecalectin; Tumor antigen HOM-HD-21
UniProt
O00182
Reactivity
Human, Mouse
Immunogen
The original antibody was generated by immunizing BALB/c mice with a recombinant c-terminus galectin-9 (residues 191 to 355 of the galectin-9 long isoform) .
Target
Galectin 9
Clonality
Monoclonal
Clone
1G3
Conjugation
Unconjugated
Field of Research
Cancer Biology
Concentration
1 mg/ml
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
The binding and binding specificity of the original format of this antibody to c-terminus Gal-9 were assessed via ELISA. Epitope mapping was also done using ELISA. Furthermore, this antibody was successfully used in WB and IHC assays (Barjon et al., 2012; PMID: 22805533) . An scFv-CAR version of this antibody with therapeutic potential was developed and described (US20230295564A1) . This antibody was successfully used to neutralize LGALS9 in a study focused on pancreatic neoplastic lesions (Quilbe et al., 2023; PMID: 38098486) . This antibody was used in a T lymphocyte proliferation assay, specifically in assessing the immunomodulatory properties of extracellular vesicles (C15SEVs) derived from nasopharyngeal carcinoma and recombinant Galectin-9S. In this assay, the antibody was used to block the impact of C15SEVs and recombinant Galectin-9 on peripheral blood mononuclear cells (Lefebvre et al., 2023; PMID: 38117000) .
Tested Applications
Blocking, ELISA, FA, IHC, NeA, WB
Host or Source
Mouse
Preservative
PBS with 0.02% Proclin 300.
Isotype
IgG

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