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GSDME Rabbit Polyclonal Antibody

CAT: 0013-GTR18608497Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18608497Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GSDME Rabbit Polyclonal Antibody
Product Name Alternative
GSDME; DFNA5; ICERE1; Gasdermin-E; Inversely correlated with estrogen receptor expression 1; ICERE-1; Non-syndromic hearing impairment protein 5 [Cleaved into: Gasdermin-E, N-terminal; GSDME-NT; Gasdermin-E, C-terminal; GSDME-CT]
UniProt
O60443
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human GSDME recombinant protein (Position: M1-K475) .
Target
Gasdermin-E
Clonality
Polyclonal
Conjugation
Unconjugated
Purification
Immunogen affinity purified.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Dilution
Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human Immunoprecipitation, 0.5-2 μg/ml, Human Flow Cytometry (Fixed), 1-3 μg/1x10^6 cells, Human ELISA, 0.1-0.5 μg/ml
Form
Lyophilized
Molecular Weight
55 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
ELISA, FC, ICC, IF, IP, WB
Host or Source
Rabbit
Preservative
Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
Isotype
Rabbit IgG

UniProtKB · O60443

Gasdermin-E

GSDME_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O60443
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
GSDME
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A4D156, B2RAX9, B3KT05, O14590, Q08AQ8, Q9UBV3
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneCytoplasmMembrane

Disease

DeafnessNon-syndromic deafnessTumor suppressor

PTM

Isopeptide bondLipoproteinPalmitateUbl conjugation

Biological process

Necrosis

Domain

TransmembraneTransmembrane beta strand

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