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VAV3 Antibody

CAT: 0247-OASG07510-100ULSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0247-OASG07510-100ULSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Vav 3 guanine nucleotide exchange factor
Gene Aliases
VAV3, Guanine nucleotide exchange factor VAV3, VAV-3
Gene ID
10451; 57257
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived between 110-190aa from human Vav3 around the non-phosphorylation site of Y173.
Target
This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/ml
Format
Liquid.// PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Reconstitution
Store at -20° C. Avoid repeated freeze/thaw cycles.
Molecular Weight
98 kDa
Fragment
IgG
Specificity
Vav3 Polyclonal Antibody detects endogenous levels of Vav3 protein.
NCBI Gene Symbol
VAV3
Host or Source
Rabbit
Protein Name
Guanine nucleotide exchange factor VAV3, VAV-3
Gene Name URL
VAV3

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