Human CD3 Antibody

• Gene Name :

  T-cell surface glycoprotein CD3 epsilon chain

• Gene Aliases :

  T3E, TCRE, IMD18

• Gene ID :

  916

• Accession Number :

  NP_000724.1

• Reactivity :

  Human

• Immunogen :

  Human peripheral blood lymphocytes from a patient with Sezary's syndrome and infant thymocytes

• Target :

  The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.

• Clonality :

  Monoclonal

• Clone :

  UCHT1

• Conjugation :

  Unconjugated

• Type :

  Monoclonal Antibody

• Applications :

  FC, IHC-F, IHC-P, ICC, IP, WB, BL

• Assay Protocol :

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration :

  0.1 mg/mL

• Dilution :

  6 cells 10 uL/106 cells 10 uL/106 cells 10 uL/106 cells 10 uL/106 cells 10 uL/106 cells 10 uL/106 cells 10 uL/106 cells 10 uL/106 cells 10 uL/106 cells666666666

• Reconstitution :

  Store at 2-8C

• Notes :

  Formerly GWB-9F0629

• Fragment :

  IgG1

• Specificity :

  CD3

• NCBI Gene Symbol :

  CD3E

• Host or Source :

  Mouse

• Protein Name :

  T-cell surface glycoprotein CD3 epsilon chain

• Gene Name URL :

  CD3E

• CAS Number :

  9007-83-4

• Nucleotide Accession Number :

  NM_000733.3