CD3 Antibody

• Gene Name:

  CD3d molecule

• Gene Aliases:

  T3D, IMD19, CD3-DELTA

• Gene ID:

  915

• Accession Number:

  NP_000723.1

• Reactivity:

  Human

• Target:

  The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK) . Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined.

• Clonality:

  Monoclonal

• Clone:

  B-B11

• Type:

  Monoclonal Antibody

• Applications:

  FC

• Purification:

  Ion exchange chromatography

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  1 ug/uL

• Bioactivity:

  Induces T lymphocyte stimulation and proliferation

• Format:

  Liquid

• Buffer:

  Phosphate-buffered saline. Sterile-filtered through 0.22 um. Carrier and preservative free

• Reconstitution:

  Stable at +2-8C for 12 months. For longer storage, freeze aliquots

• Molecular Weight:

  19 kDa

• Fragment:

  Mouse IgG1

• Specificity:

  Recognises a 20-32 kDa protein

• NCBI Gene Symbol:

  CD3

• Host or Source:

  Human

• Protein Name:

  T-cell surface glycoprotein CD3 delta chain

• Gene Name URL:

  CD3

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_000732.4