NUP133 Antibody

• Gene Name:

  Nuclear pore complex protein Nup133

• Gene Aliases:

  GAMOS8, NPHS18, hNUP133

• Gene ID:

  55746

• Accession Number:

  NP_060700.2

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Yeast nuclear preparations.

• Target:

  The nuclear pore complex (NPC) is a very large structure made up of at least 50 different proteins that span the double membrane of the nuclear envelope functioning as a gateway for macromolecular traffic between the cytoplasm and the nucleus (Nakielny and Dreyfuss,1999) . Discrete nuclear pore complex proteins or nucleoporins such as NUP98, NUP180 and p62 have been implicated in autoimmune disease and cancer. Patients with primary biliary cirrhosis (PBC) frequently produce autoantibodies against p62 and NUP180 (Wilken et al., 1993; Nesher et al., 2001) while NUP98 translocations have been found in patients with acute myelogenous leukemia (AML) .

• Clonality:

  Monoclonal

• Clone:

  39C7

• Type:

  Monoclonal Antibody

• Applications:

  IF

• Purification:

  Unpurified concentrated culture supernatant.

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  0.25 mg/ml

• Format:

  Liquid.// Contains 10 mM sodium azide. 100 ul concentrated culture supernatant. Adequate amount of material to conduct 10-mini Western blots.

• Reconstitution:

  Store at -20C ; stable for at least 1 year. Avoid freeze/thaw cycles.

• Fragment:

  1

• Specificity:

  Specificall reacts with nuclear protein complex proteins in human, mouse, rat, and yeast tissues.

• NCBI Gene Symbol:

  NUP133

• Host or Source:

  Mouse

• Protein Name:

  Nuclear pore complex protein Nup133

• Gene Name URL:

  NUP133

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_018230.2