DTX4 Antibody - N-terminal

• Gene Name:

  Deltex E3 ubiquitin ligase 4

• Gene Aliases:

  Deltex 4 homolog; deltex 4, E3 ubiquitin ligase; deltex homolog 4; deltex4; E3 ubiquitin-protein ligase DTX4; protein deltex-4; RING finger protein 155; RING-type E3 ubiquitin transferase DTX4; RNF155.

• Gene ID:

  23220

• Accession Number:

  https://www.ncbi.nlm.nih.gov/protein/NP_055992

• Reactivity:

  Human

• Immunogen:

  DTX4 antibody was raised against a 19 amino acid peptide near the center of human DTX4. The immunogen is located within amino acids 230 - 280 of DTX4.

• Target:

  Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations (By similarity) . Functions as a ubiquitin ligase protein in vivo, mediating 'Lys48'-linked polyubiquitination and promoting degradation of TBK1, targeting to TBK1 requires interaction with NLRP4.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot

• Purification:

  Affinity Purified

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  1 mg/ml

• Format:

  Liquid. DTX4 antibody is supplied in PBS containing 0.02% sodium azide.

• Reconstitution:

  For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

• Molecular Weight:

  Predicted: 68 kDa Observed: 68 kDa

• Fragment:

  IgG

• NCBI Gene Symbol:

  DTX4

• Host or Source:

  Rabbit

• Protein Name:

  E3 ubiquitin-protein ligase DTX4|E3 ubiquitin-protein ligase DTX4 isoform 1 [Homo sapiens]

• Gene Name URL:

  DTX4

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_001300727.1