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NOTUM Antibody

CAT: 0247-OAPB00936-100UGSize: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0247-OAPB00936-100UGSize:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Notum, palmitoleoyl-protein carboxylesterase
Gene Aliases
[Wnt protein] O-palmitoleoyl-L-serine hydrolase; hNOTUM; notum pectinacetylesterase homolog; palmitoleoyl-protein carboxylesterase NOTUM; protein notum homolog.
Gene ID
147111
Accession Number
https://www.ncbi.nlm.nih.gov/protein/NP_848588
Reactivity
Human|Mouse|Rat
Immunogen
NOTUM antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human NOTUM. The immunogen is located within amino acids 90 - 140 of NOTUM.
Target
Carboxylesterase that acts as a key negative regulator of the Wnt signaling pathway by specifically mediating depalmitoleoylation of WNT proteins. Serine palmitoleoylation of WNT proteins is required for efficient binding to frizzled receptors (PubMed:25731175) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/ml
Format
Liquid. NOTUM Antibody is supplied in PBS containing 0.02% sodium azide.
Reconstitution
NOTUM antibody can be stored at 4° C for three months and -20° C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
NCBI Gene Symbol
NOTUM
Host or Source
Rabbit
Protein Name
Palmitoleoyl-protein carboxylesterase NOTUM|palmitoleoyl-protein carboxylesterase NOTUM precursor [Homo sapiens]
Gene Name URL
NOTUM

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