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Rkhd2 Antibody

CAT: 0247-OAPB00774-100UGSize: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0247-OAPB00774-100UGSize:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Mex-3 RNA binding family member C
Gene Aliases
BM-013; MEX-3C; MEX3C variant 1; MEX3C variant 2; ring finger and KH domain containing 2; RING finger and KH domain-containing protein 2; RING finger protein 194; RING-type E3 ubiquitin transferase MEX3C; RKHD2; RNA-binding E3 ubiquitin-protein ligase MEX3C; RNA-binding protein MEX3C; RNF194.
Gene ID
51320
Accession Number
https://www.ncbi.nlm.nih.gov/protein/NP_057710
Reactivity
Human|Mouse|Rat
Immunogen
Rkhd2 antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human RKHD2. The immunogen is located within amino acids 540 - 590 of Rkhd2.
Target
E3 ubiquitin ligase responsible for the post-transcriptional regulation of common HLA-A allotypes. Binds to the 3' UTR of HLA-A2 mRNA, and regulates its levels by promoting mRNA decay. RNA binding is sufficient to prevent translation, but ubiquitin ligase activity is required for mRNA degradation.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Western blot
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/ml
Homology
Human; Mouse; Rat
Format
Liquid. Rkhd2 Antibody is supplied in PBS containing 0.02% sodium azide.
Reconstitution
Rkhd2 antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
NCBI Gene Symbol
MEX3C
Host or Source
Rabbit
Protein Name
RNA-binding E3 ubiquitin-protein ligase MEX3C|RNA-binding E3 ubiquitin-protein ligase MEX3C [Homo sapiens]
Gene Name URL
MEX3C

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MBS6320470-01MEX3C, CT (MEX3C, RKHD2, RNF194, RNA-binding protein MEX3C, RING finger and KH domain-containing protein 2, RING finger protein 194) (AP)
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