Products for Research Use Only
RegisterLogin

HUWE1 Antibody

CAT: 0247-OAPB00527-100UGSize: 0.1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0247-OAPB00527-100UGSize:0.1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
9007-83-4
Gene Name
HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1
Gene Aliases
ARF-binding protein 1; ARF-BP1; BJ-HCC-24 tumor antigen; E3 ubiquitin-protein ligase HUWE1; HECT domain protein LASU1; HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase; HECT, UBA and WWE domain-containing protein 1; HECTH9; HECT-type E3 ubiquitin transferase HUWE1; homologous to E6AP carboxyl terminus homologous protein 9; HSPC272; Ib772; large structure of UREB1; LASU1; Mcl-1 ubiquitin ligase E3; MRXST; MULE; upstream regulatory element-binding protein 1; UREB1; URE-B1; URE-binding protein 1.
Gene ID
10075
Accession Number
https://www.ncbi.nlm.nih.gov/protein/NP_113584
Reactivity
Human|Mouse|Rat
Immunogen
ARF-BP1 antibody was raised against a 19 amino acid synthetic peptide from near the carboxy terminus of human ARF-BP1. The immunogen is located within amino acids 4250 - 4300 of ARF-BP1.
Target
E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins. Regulates apoptosis by catalyzing the polyubiquitination and degradation of MCL1. Mediates monoubiquitination of DNA polymerase beta (POLB) at 'Lys-41', 'Lys-61' and 'Lys-81', thereby playing a role in base-excision repair. Also ubiquitinates the p53/TP53 tumor suppressor and core histones including H1, H2A, H2B, H3 and H4. Binds to an upstream initiator-like sequence in the preprodynorphin gene. Regulates neural differentiation and proliferation by catalyzing the polyubiquitination and degradation of MYCN. May regulate abundance of CDC6 after DNA damage by polyubiquitinating and targeting CDC6 to degradation. Mediates polyubiquitination of isoform 2 of PA2G4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Western blot
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/ml
Homology
Human; Mouse; Rat
Format
Liquid. ARF-BP1 Antibody is supplied in PBS containing 0.02% sodium azide.
Reconstitution
2°C to 8°C
NCBI Gene Symbol
HUWE1
Host or Source
Rabbit
Protein Name
E3 ubiquitin-protein ligase HUWE1|E3 ubiquitin-protein ligase HUWE1 [Homo sapiens]
Gene Name URL
HUWE1
Nucleotide Accession Number
NM_031407.6XM_005261965.2

Related Products

CatalogName
OKEH03504-96WHUWE1 ELISA Kit (Mouse)
OKEH01642-96WHUWE1 ELISA Kit (Human)
OKEH01643-96WHUWE1 ELISA Kit (Rat)
OKEH01642HUWE1 ELISA Kit (Human) (OKEH01642)
OKEH01643HUWE1 ELISA Kit (Rat) (OKEH01643)
OKEH03504HUWE1 ELISA Kit (Mouse) (OKEH03504)
OAMA00822-1MGWAS Antibody
OAMA00821-1MGWAS Antibody
OACD01074-100ULWAS Antibody
OASG07565-100ULWAS Antibody

Alternative Products

CatalogName
MBS9604142-01HUWE1 Antibody
A04634-2Anti-HUWE1 Antibody
MBS8531196-01HUWE1 Polyclonal Antibody
GTR18275425HUWE1 Conjugated Antibody
524153-01HUWE1

Popular Products