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PRDM1 Antibody

CAT: 0247-OAPB00471-100UGSize: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0247-OAPB00471-100UGSize:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
PR/SET domain 1
Gene Aliases
Beta-interferon gene positive regulatory domain I-binding factor; beta-interferon gene positive-regulatory domain I binding factor; BLIMP1; BLIMP-1; B-lymphocyte-induced maturation protein 1; Positive regulatory domain I-binding factor 1; PR domain 1; PR domain containing 1, with ZNF domain; PR domain zinc finger protein 1; PR domain-containing protein 1; PRDI-BF1; PRDI-binding factor-1.
Gene ID
639
Accession Number
https://www.ncbi.nlm.nih.gov/protein/NP_001189
Reactivity
Human|Mouse|Rat
Immunogen
Blimp-1 antibody was raised against a 17 amino acid synthetic peptide from near the amino terminus of human Blimp-1. The immunogen is located within amino acids 100 - 150 of Blimp-1.
Target
Transcription factor that mediates a transcriptional program in various innate and adaptive immune tissue-resident lymphocyte T cell types such as tissue-resident memory T (Trm), natural killer (trNK) and natural killer T (NKT) cells and negatively regulates gene expression of proteins that promote the egress of tissue-resident T-cell populations from non-lymphoid organs. Plays a role in the development, retention and long-term establishment of adaptive and innate tissue-resident lymphocyte T cell types in non-lymphoid organs, such as the skin and gut, but also in other nonbarrier tissues like liver and kidney, and therefore may provide immediate immunological protection against reactivating infections or viral reinfection (By similarity) . Binds specifically to the PRDI element in the promoter of the beta-interferon gene (PubMed:1851123) . Drives the maturation of B-lymphocytes into Ig secreting cells (PubMed:12626569) . Associates with the transcriptional repressor ZNF683 to chromatin at gene promoter regions (By similarity) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunohistochemistry-Paraffin|Western blot
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/ml
Homology
Human; Mouse; Rat
Format
Liquid. Blimp-1 Antibody is supplied in PBS containing 0.02% sodium azide.
Reconstitution
Blimp-1 antibody can be stored at 4C for three months and -20C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
NCBI Gene Symbol
PRDM1
Host or Source
Rabbit
Protein Name
PR domain zinc finger protein 1|PR domain zinc finger protein 1 isoform 1 [Homo sapiens]
Gene Name URL
PRDM1
Nucleotide Accession Number
NM_001198.3NM_182907.2

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