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TIRAP Antibody

CAT: 0247-OAPB00200-100UGSize: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0247-OAPB00200-100UGSize:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
TIR domain containing adaptor protein
Gene Aliases
Adapter protein wyatt; adaptor protein Wyatt; BACTS1; Mal; MyD88 adapter-like protein; MyD88-2; toll/interleukin-1 receptor domain-containing adapter protein; toll-interleukin 1 receptor (TIR) domain containing adaptor protein; Toll-like receptor adaptor protein; wyatt.
Gene ID
114609
Accession Number
https://www.ncbi.nlm.nih.gov/protein/NP_473437
Reactivity
Human|Mouse|Rat
Immunogen
TIRAP antibody was raised against a peptide corresponding to 15 amino acids near the C-terminus of mouse TIRAP. The immunogen is located within the last 50 amino acids of TIRAP.
Target
Adapter involved in TLR2 and TLR4 signaling pathways in the innate immune response. Acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, and resulting in cytokine secretion and the inflammatory response. Positively regulates the production of TNF-alpha and interleukin-6.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/ml
Homology
Human; Mouse; Rat
Format
Liquid. TIRAP Antibody is supplied in PBS containing 0.02% sodium azide.
Reconstitution
TIRAP antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight
Predicted: 24, 26 kDa Observed: 24 kDa
Notes
Formerly GWB-F1205B
NCBI Gene Symbol
TIRAP
Host or Source
Rabbit
Protein Name
Toll/interleukin-1 receptor domain-containing adapter protein|toll/interleukin-1 receptor domain-containing adapter protein [Mus musculus]
Gene Name URL
TIRAP
Nucleotide Accession Number
NM_001039661.1NM_148910.2

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