FLIP Antibody

CAT: 0247-OAPB00030-100UGSize: 0.1 mgDry Ice: NoHazardous: No
CAT#:0247-OAPB00030-100UGSize:0.1 mg
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Description
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CAS Number
9007-83-4
Gene Name
CASP8 and FADD like apoptosis regulator
Gene Aliases
CASH; CASP8 and FADD-like apoptosis regulator; CASP8AP1; caspase homolog; caspase-eight-related protein; caspase-like apoptosis regulatory protein; caspase-related inducer of apoptosis; Casper; cellular FLICE-like inhibitory protein; cFLIP; c-FLIP; c-FLIPL; c-FLIPR; c-FLIPS; CLARP; FADD-like antiapoptotic molecule 1; FLAME; FLAME1; FLAME-1; FLIP; I-FLICE; inhibitor of FLICE; MACH-related inducer of toxicity; MRIT; testis secretory sperm-binding protein Li 233m; Usurpin; usurpin beta.
Gene ID
8837
Accession Number
https://www.ncbi.nlm.nih.gov/protein/AAC51622
Reactivity
Human|Mouse|Rat
Immunogen
FLIP antibody was raised against a peptide corresponding to amino acids near the C-terminus of human FLIPaFLIPl form. The immunogen is located within the last 50 amino acids of FLIP.
Target
Apoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells. Acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. Lacks enzymatic (caspase) activity.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Western blot
Purification
Ion Exchange
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/ml
Homology
Human; Mouse; Rat
Format
Liquid. FLIP Antibody is supplied in PBS containing 0.02% sodium azide.
Reconstitution
FLIP antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight
55 kDa
Specificity
Antibody recognizes the FLIPa only.
NCBI Gene Symbol
CFLAR
Host or Source
Rabbit
Protein Name
CASP8 and FADD-like apoptosis regulator|FLICE-like inhibitory protein long form [Homo sapiens]
Gene Name URL
CFLAR

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