Products for Research Use Only
RegisterLogin

TACE Antibody

CAT: 0247-OAPB00018-100UGSize: 0.1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0247-OAPB00018-100UGSize:0.1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Click here to learn more about Aviva's By-Request Conjugation Service.//here
CAS Number
9007-83-4
Gene Name
ADAM metallopeptidase domain 17
Gene Aliases
A disintegrin and metalloproteinase 17; ADAM metallopeptidase domain 18; ADAM18; cartilage snake venom-like protease; CD156B; CSVP; disintegrin and metalloproteinase domain-containing protein 17; NISBD; NISBD1; snake venom-like protease; TACE; TNF-alpha convertase; TNF-alpha convertase enzyme; TNF-alpha converting enzyme; TNF-alpha-converting enzyme; tumor necrosis factor, alpha, converting enzyme.
Gene ID
6868
Accession Number
https://www.ncbi.nlm.nih.gov/protein/NP_003174
Reactivity
Human|Mouse|Rat
Immunogen
Anti-TACE antibody (1131) was raised against a peptide corresponding to 17 amino acids near the carboxy terminus of human TACE. The immunogen is located within the last 50 amino acids of TACE.
Target
Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including p75 TNF-receptor, interleukin 1 receptor type II, p55 TNF-receptor, transforming growth factor-alpha, L-selectin, growth hormone receptor, MUC1 and the amyloid precursor protein. Acts as an activator of Notch pathway by mediating cleavage of Notch, generating the membrane-associated intermediate fragment called Notch extracellular truncation (NEXT) . Plays a role in the proteolytic processing of ACE2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Western blot
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/ml
Homology
Human; Mouse; Rat
Format
Liquid. TACE Antibody is supplied in PBS containing 0.02% sodium azide.
Reconstitution
TACE antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight
Predicted: 93kD Observed: 93-125kD (Post-modification: 9 N-linked glycosylation)
NCBI Gene Symbol
ADAM17
Host or Source
Rabbit
Protein Name
Disintegrin and metalloproteinase domain-containing protein 17|disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
Gene Name URL
ADAM17

Related Products

CatalogName
OKRC00925-96WOKRC00925-96W - TACE ELISA Kit (Human)
OACD05984-100ULTAC3 Antibody
OACA06746-100ULTAC1 Antibody
OASA05808-100ULTAC1 Antibody
OACD05986-1MLTAC2 Antibody
OACA06745-50ULTAC1 Antibody
OAAJ07015-100ULTAC1 Antibody
OAAN01724-200ULTAC3 Antibody
OACD05984-1MLTAC3 Antibody
OACD05985-1MLTAC3 Antibody

Alternative Products

CatalogName
MBS5311223-01TACE Antibody
JOT-AP08786-01TACE Polyclonal Antibody
R32847ADAM17 Antibody / TACE
MBS851568-01ADAM17/TACE Antibody
APR10373GPolyclonal TACE Antibody
C21618-100uLTACE Antibody [A22J10]
STJ95888Anti-TACE antibody

Popular Products