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INS Antibody

CAT: 0247-OAGA08545-100ULSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0247-OAGA08545-100ULSize:100 µL
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CAS Number
9007-83-4
Gene Name
Insulin
Gene Aliases
IDDM, ILPR, IRDN, IDDM1, IDDM2, PNDM4, MODY10
Gene ID
3630
Accession Number
NP_000198.1
Reactivity
Chimpanzee
Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human Insulin. The exact sequence is proprietary.
Target
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants.
Clonality
Monoclonal
Clone
GT1455
Type
Monoclonal Antibody
Purification
Affinity purified by Protein A.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1.82 mg/ml
Format
Liquid// PBS
Reconstitution
Keep as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Molecular Weight
12 kDa
Fragment
IgG2b
NCBI Gene Symbol
INS
Host or Source
Mouse
Protein Name
Insulin
Gene Name URL
INS
Nucleotide Accession Number
NM_000207.2

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