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PRKAA2 antibody

CAT: 0247-OAGA00235-100ULSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0247-OAGA00235-100ULSize:100 µL
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CAS Number
9007-83-4
Gene Name
5'-AMP-activated protein kinase catalytic subunit alpha-2
Gene Aliases
AMPK, AMPK2, PRKAA, AMPKa2
Gene ID
5563
Accession Number
NP_006243.2
Reactivity
Human, Mouse
Immunogen
Recombinant fragment corresponding to a region within amino acids 29 and 510 of AMPK alpha 2. (Uniprot ID#P54646)
Target
The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK) . AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. [provided by RefSeq]
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
ICC, IF, IHC-FFPE, IP, WB
Purification
Purified by antigen-affinity chromatography.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
0.36 mg/ml
Homology
Bovine (99%), Chicken (96%), Pig (99%), Sheep (98%)
Format
Liquid.// PBS with 1% BSA, 20% Glycerol (pH 7) and 0.025% ProClin.
Reconstitution
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Molecular Weight
62 kDa
Fragment
IgG
NCBI Gene Symbol
PRKAA2
Host or Source
Rabbit
Protein Name
5'-AMP-activated protein kinase catalytic subunit alpha-2
Gene Name URL
PRKAA2

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