PRKAA2 antibody

• Gene Name:

  5'-AMP-activated protein kinase catalytic subunit alpha-2

• Gene Aliases:

  AMPK, AMPK2, PRKAA, AMPKa2

• Gene ID:

  5563

• Accession Number:

  NP_006243.2

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant fragment corresponding to a region within amino acids 29 and 510 of AMPK alpha 2. (Uniprot ID#P54646)

• Target:

  The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK) . AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. [provided by RefSeq]

• Clonality:

  Polyclonal

• Type:

  Polyclonal Antibody

• Applications:

  ICC, IF, IHC-FFPE, IP, WB

• Purification:

  Purified by antigen-affinity chromatography.

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  0.36 mg/ml

• Homology:

  Bovine (99%), Chicken (96%), Pig (99%), Sheep (98%)

• Format:

  Liquid.// PBS with 1% BSA, 20% Glycerol (pH 7) and 0.025% ProClin.

• Reconstitution:

  Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

• Molecular Weight:

  62 kDa

• Fragment:

  IgG

• NCBI Gene Symbol:

  PRKAA2

• Host or Source:

  Rabbit

• Protein Name:

  5'-AMP-activated protein kinase catalytic subunit alpha-2

• Gene Name URL:

  PRKAA2

• CAS Number:

  9007-83-4