Products for Research Use Only
RegisterLogin

ITGA2B Antibody

CAT: 0247-OAEE00233-100UGSize: 0.1 mg (C100)Dry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0247-OAEE00233-100UGSize:0.1 mg (C100)
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
9007-83-4
Gene Name
Integrin alpha 2b
Gene Aliases
AI172977; al; alpha IIb; alphaIIb; CD41; CD41B; Gp; GP IIb; GPalpha IIb; GpIIb; integrin alpha-IIb; platelet glycoprotein IIb of IIb/II Ia complex; platelet membrane glycoprotein IIb.
Gene ID
16399
Accession Number
NP_000410.2
Reactivity
Mouse
Immunogen
Murine platelets
Target
Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.
Clonality
Monoclonal
Clone
MWReg30
Type
Monoclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Flow cytometry|Immunohistochemistry-Frozen|Immunohistochemistry-Paraffin|Immunoprecipitation
Purification
Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/ml
Format
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Buffer
Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Reconstitution
2°C to 8°C
Fragment
IgG1
Specificity
The rat monoclonal antibody MWReg30 recognizes CD41 (GPIIb), a transmembrane glycoprotein (integrin family) composed of two chains GPIIb alpha (heavy chain; 120 kDa) and GPIIb beta (light chain; 23 kDa) . CD41 is mainly expressed on platelets and megakaryocytes.
NCBI Gene Symbol
Itga2b
Host or Source
Rat
Protein Name
Integrin alpha-IIb
Gene Name URL
Itga2b
Nucleotide Accession Number
NM_000419.3

Related Products

CatalogName
OPCA02696-100UGITGA2B Recombinant Protein
OPCD04564-200UGITGA2B Recombinant Protein
OPCA02696-20UGITGA2B Recombinant Protein
OPCA01668-100UGITGA2B Recombinant Protein
OCOA17407-20UGITGA2B Protein Lysate
OPCA01668-20UGITGA2B Recombinant Protein
OPCD04564-50UGITGA2B Recombinant Protein
OPCA01668-1MGITGA2B Recombinant Protein
OPCD04564-10UGITGA2B Recombinant Protein
OKCD06583-96WITGA2B ELISA Kit (Human)

Alternative Products

CatalogName
GWB-MX027IITGA2B Antibody

Popular Products