RegisterLogin

CD14 antibody

CAT: 0247-OAEE00081-100UGSize: 0.1 mg (C100)Dry Ice: NoHazardous: No
CAT#:0247-OAEE00081-100UGSize:0.1 mg (C100)
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
CAS Number
9007-83-4
Gene Name
CD14 molecule
Gene Aliases
Monocyte differentiation antigen CD14; myeloid cell-specific leucine-rich glycoprotein.
Gene ID
929
Accession Number
NP_000582.1NP_001035110.1NP_001167575.1NP_001167576.1
Reactivity
Human|Non-human Primate
Immunogen
A crude mixture of human urinary proteins precipitated by ammonium sulphate from the urine of a patient suffering from proteinuria.
Target
Coreceptor for bacterial lipopolysaccharide (PubMed:1698311, PubMed:23264655) . In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS) (PubMed:20133493, PubMed:23264655) . Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (PubMed:8612135) . Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway (PubMed:16880211) . Binds electronegative LDL (LDL (-) ) and mediates the cytokine release induced by LDL (-) (PubMed:23880187) .
Clonality
Monoclonal
Clone
MEM-18
Type
Monoclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Flow cytometry|Functional assay|Immunoprecipitation|Western blot
Purification
Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/ml
Format
Phosphate buffered saline (PBS), pH 7.4
Buffer
Azide free phosphate buffered saline (PBS), approx. pH 7.4; 0.2 um filter sterilized. Endotoxin level is less than 0.01 EU/ug of the protein, as determined by the LAL test.
Reconstitution
2°C to 8°C
Fragment
IgG1
Specificity
HLDA III; WS Code M 253 HLDA IV; WS Code M 314 HLDA V; WS Code M MA087 HLDA VI; WS Code M MA95//
NCBI Gene Symbol
CD14
Host or Source
Mouse
Protein Name
Monocyte differentiation antigen CD14
Gene Name URL
CD14
Nucleotide Accession Number
NM_000591.3NM_001040021.2NM_001174104.1NM_001174105.1

Related Products

CatalogName
OAAI00676-100UGAnti-CD14 Monoclonal Antibody
OPPA01422-10UGCD14 Protein
OPPA01423-2UGCD14 Protein
OPCD01981-10UGCD14 Recombinant Protein
OPCD01982-10UGCD14 Recombinant Protein
OPCD01981-200UGCD14 Recombinant Protein
OPCD01980-200UGCD14 Recombinant Protein
OPCD01980-10UGCD14 Recombinant Protein
OPCD01980-50UGCD14 Recombinant Protein
OPCD01981-50UGCD14 Recombinant Protein

Alternative Products

CatalogName
V0016-01CD14 [ABT-CD14] Antibody
MBS9510621-01Anti-CD14 Antibody [ABT-CD14]
MBS859660-01CD14 Antibody

Popular Products