IL33 Antibody

• Gene Name :

  Interleukin 33

• Gene Aliases :

  C9orf26; DVS27; DVS27-related protein; IL1F11; interleukin-1 family member 11; interleukin-33; NFEHEV; NF-HEV; nuclear factor for high endothelial venules; nuclear factor from high endothelial venules.

• Gene ID :

  90865

• Accession Number :

  NP_001186569.1NP_001186570.1NP_254274.1XP_005251683.1XP_005251684.1

• Reactivity :

  Human|Mouse|Rat

• Immunogen :

  Recombinant human soluble IL-33 (interleukin-33) (aa 112-270)

• Target :

  Cytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells (PubMed:16286016) . Involved in the maturation of Th2 cells inducing the secretion of T-helper type 2-associated cytokines. Also involved in activation of mast cells, basophils, eosinophils and natural killer cells. Acts as a chemoattractant for Th2 cells, and may function as an "alarmin", that amplifies immune responses during tissue injury (PubMed:17853410, PubMed:18836528) .

• Clonality :

  Polyclonal

• Type :

  Polyclonal Antibody

• Applications :

  Enzyme-linked immunosorbent assay|Western blot

• Assay Protocol :

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration :

  1mg/ml

• Format :

  Liquid. In PBS containing 0.02% sodium azide.

• Reconstitution :

  Long Term Storage : //-20C Short Term Storage : //+4C Handling : //After opening, prepare aliquots and store at -20C. Avoid freeze/thaw cycles. Stable for at least 1 year after receipt when stored at -20C.Short Term Storage : //+4C Handling : //After opening, prepare aliquots and store at -20C. Avoid freeze/thaw cycles. Stable for at least 1 year after receipt when stored at -20C.Handling : //After opening, prepare aliquots and store at -20C. Avoid freeze/thaw cycles. Stable for at least 1 year after receipt when stored at -20C.

• Specificity :

  Recognizes human, mouse and rat pro-IL-33 and mature IL-33.

• NCBI Gene Symbol :

  IL33

• Host or Source :

  Rabbit

• Protein Name :

  Interleukin-33

• Gene Name URL :

  IL33

• CAS Number :

  9007-83-4

• Nucleotide Accession Number :

  NM_001199640.1NM_001199641.1NM_033439.3XM_005251626.3XM_005251627.1