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IL33 Antibody

CAT: 0247-OAED00263-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0247-OAED00263-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Interleukin 33
Gene Aliases
C9orf26; DVS27; DVS27-related protein; IL1F11; interleukin-1 family member 11; interleukin-33; NFEHEV; NF-HEV; nuclear factor for high endothelial venules; nuclear factor from high endothelial venules.
Gene ID
90865
Accession Number
NP_001186569.1NP_001186570.1NP_254274.1XP_005251683.1XP_005251684.1
Reactivity
Human|Mouse|Rat
Immunogen
Recombinant human soluble IL-33 (interleukin-33) (aa 112-270)
Target
Cytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells (PubMed:16286016) . Involved in the maturation of Th2 cells inducing the secretion of T-helper type 2-associated cytokines. Also involved in activation of mast cells, basophils, eosinophils and natural killer cells. Acts as a chemoattractant for Th2 cells, and may function as an "alarmin", that amplifies immune responses during tissue injury (PubMed:17853410, PubMed:18836528) .
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Western blot
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1mg/ml
Format
Liquid. In PBS containing 0.02% sodium azide.
Reconstitution
Long Term Storage : //-20C Short Term Storage : //+4C Handling : //After opening, prepare aliquots and store at -20C. Avoid freeze/thaw cycles. Stable for at least 1 year after receipt when stored at -20C.Short Term Storage : //+4C Handling : //After opening, prepare aliquots and store at -20C. Avoid freeze/thaw cycles. Stable for at least 1 year after receipt when stored at -20C.Handling : //After opening, prepare aliquots and store at -20C. Avoid freeze/thaw cycles. Stable for at least 1 year after receipt when stored at -20C.
Specificity
Recognizes human, mouse and rat pro-IL-33 and mature IL-33.
NCBI Gene Symbol
IL33
Host or Source
Rabbit
Protein Name
Interleukin-33
Gene Name URL
IL33
Nucleotide Accession Number
NM_001199640.1NM_001199641.1NM_033439.3XM_005251626.3XM_005251627.1

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