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IL-7 Antibody

CAT: 0247-OADB00381-1MGSize: 1 mgDry Ice: NoHazardous: No
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CAT#:0247-OADB00381-1MGSize:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Interleukin 7
Gene Aliases
IL-7
Gene ID
3574
Accession Number
NP_000871.1
Reactivity
Human
Target
The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V (D) J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed.
Clonality
Monoclonal
Clone
B-N18
Type
Monoclonal Antibody
Purification
Ion exchange chromatography
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/ml
Bioactivity
This Antibody can be used as Capture in a human IL-7 sandwich Immunoassay to detect human IL-7 in combination with biotinylated human IL-7 Detection Antibody
Format
Lyophilized
Reconstitution
Store at +2-8C for 12 months. For longer storage, freeze aliquots at -20C
Molecular Weight
20 kDa
Fragment
Mouse IgG1
Specificity
Recognises both natural and recombinant IL-7
NCBI Gene Symbol
IL-7
Host or Source
Mouse
Protein Name
Interleukin-7
Gene Name URL
IL-7
Nucleotide Accession Number
NM_000880.3

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