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IL-6 Antibody

CAT: 0247-OADB00375-500UGSize: 500 µgDry Ice: NoHazardous: No
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CAT#:0247-OADB00375-500UGSize:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Interleukin 6
Gene Aliases
CDF, HGF, HSF, BSF2, IL-6, BSF-2, IFNB2, IFN-beta-2
Gene ID
3569
Accession Number
NP_000591.1
Reactivity
Human
Target
This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Alternative splicing results in multiple transcript variants.
Clonality
Monoclonal
Clone
B-F6
Type
Monoclonal Antibody
Purification
Ion exchange chromatography
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 ug/uL
Bioactivity
No effect on IL-6 induced proliferation on B9 cell line
Format
Lyophilized
Buffer
Phosphate-buffered saline. Sterile-filtered through 0.22 um. Carrier and preservative free
Reconstitution
Store at +2-8C for 12 months. For longer storage, freeze aliquots
Molecular Weight
24 kDa
Fragment
Mouse IgG1
Specificity
Recognises both natural and recombinant human IL-6
NCBI Gene Symbol
IL-6
Host or Source
Mouse
Protein Name
Interleukin-6
Gene Name URL
IL-6
Nucleotide Accession Number
NM_000600.4

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