CD62P Antibody

• Gene Name:

  Selectin P

• Gene Aliases:

  CD62, GRMP, PSEL, CD62P, GMP140, LECAM3, PADGEM

• Gene ID:

  6403

• Accession Number:

  NP_002996.2

• Reactivity:

  Human

• Target:

  This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented.

• Clonality:

  Monoclonal

• Clone:

  B-F46

• Type:

  Monoclonal Antibody

• Applications:

  FC

• Purification:

  Ion exchange chromatography

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  1 ug/uL

• Bioactivity:

  Recognises soluble and membrane antigen

• Format:

  Liquid

• Buffer:

  Phosphate-buffered saline. Sterile-filtered through 0.22 um. Carrier and preservative free

• Reconstitution:

  Stable at +2-8C for 12 months. For longer storage, freeze aliquots

• Molecular Weight:

  91 kDa

• Fragment:

  Mouse IgG1 Kappa light chain

• Specificity:

  Recognises CD62P, a 140 kDa single chain type I transmembrane glycoprotein present in secretory α-granules in platelets, Weibel-Palade bodies in endothelial cells & megakaryocytes.

• NCBI Gene Symbol:

  CD62P

• Host or Source:

  Human

• Protein Name:

  P-selectin

• Gene Name URL:

  CD62P

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_003005.3