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CD62E Antibody

CAT: 0247-OADB00236-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0247-OADB00236-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Selectin E
Gene Aliases
ELAM, ESEL, CD62E, ELAM1, LECAM2
Gene ID
6401
Accession Number
NP_000441.2
Reactivity
Human
Target
The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis.
Clonality
Monoclonal
Clone
B-S3
Type
Monoclonal Antibody
Purification
Ion exchange chromatography
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Bioactivity
ELISA Detection Antibody. This Antibody can be used as Detection in a human CD62E sandwich Immunoassay to detect human CD62E in combination with human CD62E Capture Antibody (Cat n° 879.530.001) . The suggested coating concentration range below should be optimised by each laboratory for each application.
Format
Lyophilized
Buffer
Phosphate-buffered saline. With 1% BSA and 0.09% Sodium Azide*.
Reconstitution
Store at +2-8C for 12 months. For longer storage, freeze aliquots at -20C
Molecular Weight
67 kDa
Fragment
Mouse IgG1
Specificity
Recognises the Endothelial Leucocyte Adhesion Molecule-1 (ELAM-1), E-Selectin, a 97 kDa protein
NCBI Gene Symbol
CD62E
Host or Source
Human
Protein Name
E-selectin
Gene Name URL
CD62E
Nucleotide Accession Number
NM_000450.2

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