CD62E Antibody

• Gene Name:

  Selectin E

• Gene Aliases:

  ELAM, ESEL, CD62E, ELAM1, LECAM2

• Gene ID:

  6401

• Accession Number:

  NP_000441.2

• Reactivity:

  Human

• Target:

  The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis.

• Clonality:

  Monoclonal

• Clone:

  B-S3

• Type:

  Monoclonal Antibody

• Purification:

  Ion exchange chromatography

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Bioactivity:

  ELISA Detection Antibody. This Antibody can be used as Detection in a human CD62E sandwich Immunoassay to detect human CD62E in combination with human CD62E Capture Antibody (Cat n° 879.530.001) . The suggested coating concentration range below should be optimised by each laboratory for each application.

• Format:

  Lyophilized

• Buffer:

  Phosphate-buffered saline. With 1% BSA and 0.09% Sodium Azide*.

• Reconstitution:

  Store at +2-8C for 12 months. For longer storage, freeze aliquots at -20C

• Molecular Weight:

  67 kDa

• Fragment:

  Mouse IgG1

• Specificity:

  Recognises the Endothelial Leucocyte Adhesion Molecule-1 (ELAM-1), E-Selectin, a 97 kDa protein

• NCBI Gene Symbol:

  CD62E

• Host or Source:

  Human

• Protein Name:

  E-selectin

• Gene Name URL:

  CD62E

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_000450.2