CD263 Antibody

• Gene Name:

  Tumor necrosis factor receptor superfamily member 10c

• Gene Aliases:

  LIT, DCR1, TRID, CD263, TRAILR3, TRAIL-R3, DCR1-TNFR

• Gene ID:

  8794

• Accession Number:

  NP_003832.2

• Reactivity:

  Human

• Target:

  The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL.

• Clonality:

  Monoclonal

• Clone:

  B-D44

• Type:

  Monoclonal Antibody

• Applications:

  FC

• Purification:

  Ion exchange chromatography

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  200 tests/2mL

• Format:

  Liquid

• Buffer:

  Phosphate-buffered saline with 1% BSA and 0.1% sodium azide

• Reconstitution:

  Stable at +2-8C for 12 months. For longer storage freeze aliquots

• Molecular Weight:

  27 kDa

• Fragment:

  IgG1

• Specificity:

  Recognises DcR1 (CD263), a 75.90kDa protein

• NCBI Gene Symbol:

  CD263

• Host or Source:

  Human

• Protein Name:

  Tumor necrosis factor receptor superfamily member 10C

• Gene Name URL:

  CD263

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_003841.3