CD261 Antibody

• Gene Name :

  Tumor necrosis factor receptor superfamily member 10a

• Gene Aliases :

  DR4, APO2, CD261, TRAILR1, TRAILR-1

• Gene ID :

  8797

• Accession Number :

  NP_003835.3

• Reactivity :

  Human

• Target :

  The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein.

• Clonality :

  Monoclonal

• Clone :

  B-N36

• Type :

  Monoclonal Antibody

• Purification :

  Ion exchange chromatography

• Assay Protocol :

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration :

  1 ug/uL

• Bioactivity :

  Neutralizes TRAIL induced apoptosis on HEL cell line

• Format :

  Lyophilized

• Buffer :

  Phosphate-buffered saline. Sterile-filtered through 0.22 um and treated to remove endotoxins. Carrier and preservative free

• Reconstitution :

  Stable at +2-8C for 12 months. For longer storage, freeze aliquots

• Molecular Weight :

  50 kDa

• Fragment :

  IgG1

• Specificity :

  Recognises a 43-46 kDa protein

• NCBI Gene Symbol :

  CD261

• Protein Name :

  Tumor necrosis factor receptor superfamily member 10A

• Gene Name URL :

  CD261

• CAS Number :

  9007-83-4

• Nucleotide Accession Number :

  NM_003844.3