CD261 Antibody

• Gene Name:

  Tumor necrosis factor receptor superfamily member 10a

• Gene Aliases:

  DR4, APO2, CD261, TRAILR1, TRAILR-1

• Gene ID:

  8797

• Accession Number:

  NP_003835.3

• Reactivity:

  Human

• Target:

  The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein.

• Clonality:

  Monoclonal

• Clone:

  B-N36

• Type:

  Monoclonal Antibody

• Purification:

  Ion exchange chromatography

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  1 ug/uL

• Bioactivity:

  Neutralizes TRAIL induced apoptosis on HEL cell line

• Format:

  Lyophilized

• Buffer:

  Phosphate-buffered saline. Sterile-filtered through 0.22 um and treated to remove endotoxins. Carrier and preservative free

• Reconstitution:

  Stable at +2-8C for 12 months. For longer storage, freeze aliquots

• Molecular Weight:

  50 kDa

• Fragment:

  IgG1

• Specificity:

  Recognises a 43-46 kDa protein

• NCBI Gene Symbol:

  CD261

• Protein Name:

  Tumor necrosis factor receptor superfamily member 10A

• Gene Name URL:

  CD261

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_003844.3