UACA Antibody

CAT: 0247-OACD08095-100ULSize: 100 µLDry Ice: NoHazardous: No
CAT#:0247-OACD08095-100ULSize:100 µL
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CAS Number
9007-83-4
Gene Name
Uveal autoantigen with coiled-coil domains and ankyrin repeats
Gene Aliases
Nuclear membrane binding protein; NUCLING; uveal autoantigen with coiled-coil domains and ankyrin repeats.
Gene ID
55075
Accession Number
NP_001008225.1
Reactivity
Bovine|Human
Immunogen
Range: Ala29 - Glu209
Target
Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1 (By similarity) .
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot
Purification
Affinity Purified; Protein A Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Format
Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Reconstitution
2°C to 8°C|-20°C
Molecular Weight
162 kDa
Fragment
IgG
Specificity
The antibody is a rabbit polyclonal antibody raised against UACA. It has been selected for its ability to recognize UACA in immunohistochemical staining and western blotting.
NCBI Gene Symbol
UACA
Host or Source
Rabbit
Protein Name
Uveal autoantigen with coiled-coil domains and ankyrin repeats
Gene Name URL
UACA
Nucleotide Accession Number
NM_001008224

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