PPM1A Antibody

CAT: 0247-OACD06666-100ULSize: 100 µLDry Ice: NoHazardous: No
CAT#:0247-OACD06666-100ULSize:100 µL
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CAS Number
9007-83-4
Gene Name
Protein phosphatase, Mg2+/Mn2+ dependent 1A
Gene Aliases
PP2CA; PP2Calpha; PP2C-ALPHA; protein phosphatase 1A; Protein phosphatase 2C isoform alpha; Protein phosphatase IA.
Gene ID
5494
Accession Number
NP_066283.1
Reactivity
Human|Mouse|Porcine|Rat
Immunogen
Range: Gly2 - Try382
Target
Enzyme with a broad specificity. Negatively regulates TGF-beta signaling through dephosphorylating SMAD2 and SMAD3, resulting in their dissociation from SMAD4, nuclear export of the SMADs and termination of the TGF-beta-mediated signaling. Dephosphorylates PRKAA1 and PRKAA2. Plays an important role in the termination of TNF-alpha-mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot
Purification
Affinity Purified; Protein A Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Format
Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Reconstitution
2°C to 8°C|-20°C
Molecular Weight
36 kDa
Fragment
IgG
Specificity
The antibody is a rabbit polyclonal antibody raised against PPM1A. It has been selected for its ability to recognize PPM1A in immunohistochemical staining and western blotting.
NCBI Gene Symbol
PPM1A
Host or Source
Rabbit
Protein Name
Protein phosphatase 1A
Gene Name URL
PPM1A
Nucleotide Accession Number
NM_021003

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