MAEA Antibody

• Gene Name:

  Macrophage erythroblast attacher, E3 ubiquitin ligase

• Gene Aliases:

  Cell proliferation-inducing gene 5 protein; E3 ubiquitin-protein transferase MAEA; EMLP; EMP; erythroblast macrophage protein; GID complex subunit 9, FYV10 homolog; GID9; HLC-10; human lung cancer oncogene 10 protein; lung cancer-related protein 10; P44EMLP; PIG5.

• Gene ID:

  10296

• Accession Number:

  NP_001017405.1

• Reactivity:

  Human|Mouse|Rat

• Immunogen:

  Range: Cys136 - Pro379

• Target:

  Plays a role in erythroblast enucleation and in the development of the mature macrophages. Mediates the attachment of erythroid cell to mature macrophages, in correlation with the presence of MAEA at cell surface of mature macrophages; This MAEA-mediated contact inhibits erythroid cells apoptosis. Participates in erythroblastic island formation, which is the functional unit of definitive erythropoiesis. Associates with F-actin to regulate actin distribution in erythroblasts and macrophages. May contribute to nuclear architecture and cells division events.

• Clonality:

  Polyclonal

• Type:

  Polyclonal Antibody

• Applications:

  Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot

• Purification:

  Affinity Purified; Protein A Purified

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  0.5 mg/ml

• Format:

  Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.

• Reconstitution:

  2°C to 8°C|-20°C

• Molecular Weight:

  27 kDa

• Fragment:

  IgG

• Specificity:

  The antibody is a rabbit polyclonal antibody raised against MAEA. It has been selected for its ability to recognize MAEA in immunohistochemical staining and western blotting.

• NCBI Gene Symbol:

  MAEA

• Host or Source:

  Rabbit

• Protein Name:

  Macrophage erythroblast attacher

• Gene Name URL:

  MAEA

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_001017405