IREB2 Antibody

CAT: 0247-OACD04836-1MLSize: 1 mLDry Ice: NoHazardous: No
CAT#:0247-OACD04836-1MLSize:1 mL
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CAS Number
9007-83-4
Gene Name
Iron responsive element binding protein 2
Gene Aliases
IRE-BP 2; iron regulatory protein 2; iron-responsive element-binding protein 2; Irp2.
Gene ID
64831
Accession Number
NP_074054.2
Reactivity
Human|Mouse|Rat
Immunogen
Range: Met1 - His343
Target
RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot
Purification
Affinity Purified; Protein A Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Format
Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Reconstitution
2°C to 8°C|-20°C
Molecular Weight
105 kDa
Fragment
IgG
Specificity
The antibody is a rabbit polyclonal antibody raised against IREB2. It has been selected for its ability to recognize IREB2 in immunohistochemical staining and western blotting.
NCBI Gene Symbol
Ireb2
Host or Source
Rabbit
Protein Name
Iron-responsive element-binding protein 2
Gene Name URL
Ireb2
Nucleotide Accession Number
NM_022863

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