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DLD Antibody

CAT: 0247-OACD03070-1MLSize: 1 mLDry Ice: NoHazardous: No
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CAT#:0247-OACD03070-1MLSize:1 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Dihydrolipoamide dehydrogenase
Gene Aliases
Branched chain alpha-keto acid dehydrogenase complex subunit E3; Dihydrolipoamide dehydrogenase; dihydrolipoyl dehydrogenase, mitochondrial.
Gene ID
13382
Accession Number
NP_031887.2
Reactivity
Mouse
Immunogen
Range: Thr45 - Lys271
Target
Lipoamide dehydrogenase is a component of the glycine cleavage system as well as an E3 component of three alpha-ketoacid dehydrogenase complexes (pyruvate-, alpha-ketoglutarate-, and branched-chain amino acid-dehydrogenase complex) (By similarity) . The 2-oxoglutarate dehydrogenase complex is mainly active in the mitochondrion (By similarity) . A fraction of the 2-oxoglutarate dehydrogenase complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl-CoA to histone succinyltransferase KAT2A (By similarity) . In monomeric form may have additional moonlighting function as serine protease (PubMed:17404228) . Involved in the hyperactivation of spermatazoa during capacitation and in the spermatazoal acrosome reaction (By similarity) .
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot
Purification
Affinity Purified; Protein A Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Format
Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Reconstitution
2°C to 8°C|-20°C
Molecular Weight
54 kDa
Fragment
IgG
Specificity
The antibody is a rabbit polyclonal antibody raised against DLD. It has been selected for its ability to recognize DLD in immunohistochemical staining and western blotting.
NCBI Gene Symbol
Dld
Host or Source
Rabbit
Protein Name
Dihydrolipoyl dehydrogenase, mitochondrial
Gene Name URL
Dld
Nucleotide Accession Number
NM_007861