APLN Antibody

• Gene Name :

  Apelin

• Gene Aliases :

  Apel; apelin; apelin, AGTRL1 ligand; APJ endogenous ligand.

• Gene ID :

  58812

• Reactivity :

  Mouse|Rat

• Immunogen :

  Range: Ala19 - Phe77

• Target :

  Endogenous ligand for the apelin receptor (APLNR) (PubMed:11336787, PubMed:11359874, PubMed:26611206) . Drives internalization of the apelin receptor (PubMed:11359874) . Apelin-36 dissociates more hardly than (pyroglu) apelin-13 from APLNR (PubMed:11336787) . Hormone involved in the regulation of cardiac precursor cell movements during gastrulation and heart morphogenesis (By similarity) . Has an inhibitory effect on cytokine production in response to T-cell receptor/CD3 cross-linking; the oral intake of apelin in the colostrum and the milk might therefore modulate immune responses in neonates (By similarity) . Plays a role in early coronary blood vessels formation (By similarity) . Mediates myocardial contractility in an ERK1/2-dependent manner (PubMed:26611206) . May also have a role in the central control of body fluid homeostasis by influencing vasopressin release and drinking behavior (PubMed:10617103, PubMed:11359874) .

• Clonality :

  Polyclonal

• Type :

  Polyclonal Antibody

• Applications :

  Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot

• Purification :

  Affinity Purified; Protein A Purified

• Assay Protocol :

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration :

  0.5 mg/ml

• Format :

  Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.

• Reconstitution :

  2°C to 8°C|-20°C

• Fragment :

  IgG

• Specificity :

  The antibody is a rabbit polyclonal antibody raised against APLN. It has been selected for its ability to recognize APLN in immunohistochemical staining and western blotting.

• NCBI Gene Symbol :

  Apln

• Host or Source :

  Rabbit

• Protein Name :

  Apelin

• Gene Name URL :

  Apln

• CAS Number :

  9007-83-4