PIDD1 Antibody

CAT: 0247-OACD01031-100ULSize: 100 µLDry Ice: NoHazardous: No
CAT#:0247-OACD01031-100ULSize:100 µL
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CAS Number
9007-83-4
Gene Name
P53-induced death domain protein 1
Gene Aliases
Leucine-rich repeat and death domain-containing protein; leucine-rich repeats and death domain containing; LRDD; p53-induced death domain-containing protein 1; p53-induced protein with a death domain; PIDD.
Gene ID
55367
Accession Number
NP_665893.2
Reactivity
Human|Rat
Immunogen
Recombinant LRDD (Phe694 - Arg885) expressed in E.coli.
Target
Promotes apoptosis downstream of the tumor suppressor as component of the DNA damage/stress response pathway that connects p53/TP53 to apoptosis. Associates with NEMO/IKBKG and RIP1 and enhances sumoylation and ubiquitination of NEMO/IKBKG which is important for activation of the transcription factor NF-kappa-B. Associates with CASP2/caspase-2 and CRADD/RAIDD, and induces activation of CASP2 which an important regulator in apoptotic pathways.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot
Purification
Affinity Purified; Protein A Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
0.93 mg/ml
Format
Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Reconstitution
2°C to 8°C|-20°C
Molecular Weight
33 kDa
Fragment
IgG
Specificity
The antibody is a rabbit polyclonal antibody raised against LRDD. It has been selected for its ability to recognize LRDD in immunohistochemical staining and western blotting.
NCBI Gene Symbol
PIDD1
Host or Source
Rabbit
Protein Name
P53-induced death domain-containing protein 1
Gene Name URL
PIDD1
Nucleotide Accession Number
NM_145886

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