CBR1 Antibody

9007-83-4

Carbonyl reductase 1

15-hydroxyprostaglandin dehydrogenase;15-hydroxyprostaglandin dehydrogenase [NADP (+) ];20-beta-hydroxysteroid dehydrogenase; AW261796; C; carbonyl reductase [NADPH] 1; Carbonyl reductase [NADPH] 1 (NADPH-dependent carbonyl reductase 1) ; Cbr; CR; NADPH-dependent carbonyl reductase 1; PG-9-KR; prostaglandin 9-ketoreductase; prostaglandin-E (2) 9-reductase.

12408

NP_031646.2

Human|Mouse|Rat

Range: Asn66 - Asp271

NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2-alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S-nitrosoglutathione (By similarity) .

Polyclonal Antibody

Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot

Affinity Purified; Protein A Purified

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

0.5 mg/ml

Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

2°C to 8°C|-20°C

31 kDa

IgG

The antibody is a rabbit polyclonal antibody raised against CBR1. It has been selected for its ability to recognize CBR1 in immunohistochemical staining and western blotting.

Cbr1

Rabbit

Carbonyl reductase [NADPH] 1

Cbr1