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PPP1R15A Antibody

CAT: 0247-OACD00846-100ULSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0247-OACD00846-100ULSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Protein phosphatase 1, regulatory subunit 15A
Gene Aliases
Gadd34; growth arrest and DNA damage-inducible protein GADD34; Myd116; myeloid differentiation primary response gene 116; myeloid differentiation primary response protein MyD116 homolog; Peg-3; progression elevated gene 3 protein; protein phosphatase 1 regulatory subunit 15A; protein phosphatase 1, regulatory (inhibitor) subunit 15A; RGD1624209.
Gene ID
171071
Accession Number
NP_598230.2
Reactivity
Rat
Immunogen
Range: Glu335 - Gly578
Target
Recruits the serine/threonine-protein phosphatase PP1 to dephosphorylate the translation initiation factor eIF-2A/EIF2S1, thereby reversing the shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress. Down-regulates the TGF-beta signaling pathway by promoting dephosphorylation of TGFB1 by PP1. May promote apoptosis by inducing TP53 phosphorylation on 'Ser-15'.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot
Purification
Affinity Purified; Protein A Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Format
Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Reconstitution
2°C to 8°C|-20°C
Molecular Weight
64 kDa
Fragment
IgG
Specificity
The antibody is a rabbit polyclonal antibody raised against PPP1R15A. It has been selected for its ability to recognize PPP1R15A in immunohistochemical staining and western blotting.
NCBI Gene Symbol
Ppp1r15a
Host or Source
Rabbit
Protein Name
Protein phosphatase 1 regulatory subunit 15A
Gene Name URL
Ppp1r15a
Nucleotide Accession Number
NM_133546

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