TBC1D7 Antibody

• Gene Name :

  TBC1 domain family member 7|TBC1D7-LOC100130357 readthrough

• Gene Aliases :

  Cell migration-inducing protein 23; MGCPH; PIG51; TBC1 domain family member 7; TBC7; TS complex subunit 3.

• Gene ID :

  107080638|51256

• Accession Number :

  NP_001137436

• Reactivity :

  Human

• Immunogen :

  Recombinant Human TBC1 domain family member 7 protein (1-293AA)

• Target :

  Component of the TSC-TBC complex, that contains TBC1D7 in addition to the TSC1-TSC2 complex and consists of the functional complex possessing GTPase-activating protein (GAP) activity toward RHEB in response to alterations in specific cellular growth conditions. The small GTPase RHEB is a direct activator of the protein kinase activity of mTORC1 and the TSC-TBC complex acts as a negative regulator of mTORC1 signaling cascade by acting as a GAP for RHEB. Participates in the proper sensing of growth factors and glucose, but not amino acids, by mTORC1. It is unclear whether TBC1D7 acts as a GTPase-activating protein and additional studies are required to answer this question.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry

• Purification :

  Protein G Purified

• Assay Protocol :

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Format :

  Liquid

• Reconstitution :

  -20°C or -80°C

• Fragment :

  IgG

• NCBI Gene Symbol :

  TBC1D7|TBC1D7-LOC100130357

• Host or Source :

  Rabbit

• Protein Name :

  TBC1 domain family member 7

• Gene Name URL :

  TBC1D7|TBC1D7-LOC100130357

• CAS Number :

  9007-83-4

• Nucleotide Accession Number :

  NM_001143964