Products for Research Use Only
RegisterLogin

RNF4 Antibody

CAT: 0247-OACA09461-50UGSize: 50 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0247-OACA09461-50UGSize:50 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
9007-83-4
Gene Name
Ring finger protein 4
Gene Aliases
E3 ubiquitin ligase RNF4; E3 ubiquitin-protein ligase RNF4; RES4-26; RING finger protein 4; RING-type E3 ubiquitin transferase RNF4; SLX5; small nuclear RING finger protein; SNURF.
Gene ID
6047
Accession Number
NP_001171938
Reactivity
Human
Immunogen
Recombinant Human E3 ubiquitin-protein ligase RNF4 protein (1-103AA)
Target
E3 ubiquitin-protein ligase which binds polysumoylated chains covalently attached to proteins and mediates 'Lys-6'-, 'Lys-11'-, 'Lys-48'- and 'Lys-63'-linked polyubiquitination of those substrates and their subsequent targeting to the proteasome for degradation. Regulates the degradation of several proteins including PML and the transcriptional activator PEA3. Involved in chromosome alignment and spindle assembly, it regulates the kinetochore CENPH-CENPI-CENPK complex by targeting polysumoylated CENPI to proteasomal degradation. Regulates the cellular responses to hypoxia and heat shock through degradation of respectively EPAS1 and PARP1. Alternatively, it may also bind DNA/nucleosomes and have a more direct role in the regulation of transcription for instance enhancing basal transcription and steroid receptor-mediated transcriptional activation.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry
Purification
Protein G Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
-20°C or -80°C
Fragment
IgG
NCBI Gene Symbol
RNF4
Host or Source
Rabbit
Protein Name
E3 ubiquitin-protein ligase RNF4
Gene Name URL
RNF4
Nucleotide Accession Number
NM_001185009

Related Products

CatalogName
OCOA20948-20UGRNF4 Protein Lysate
OCOA13874-20UGRNF4 Protein Lysate
OKEI00541RNF4 ELISA Kit (Mouse) (OKEI00541)
OKEI00235RNF4 ELISA Kit (Human) (OKEI00235)
OKEI00833RNF4 ELISA Kit (Rat) (OKEI00833)
OKEI00235-96WOKEI00235-96W - RNF4 ELISA Kit (Human)
OKEI00833-96WOKEI00833-96W - RNF4 ELISA Kit (Rat)
OKEI00541-96WOKEI00541-96W - RNF4 ELISA Kit (Mouse)
OAAL00286-100UGRNF2 Antibody
OAAN02209-200ULRNF8 Antibody

Alternative Products

CatalogName
AM8684bRNF4 Antibody
M02875-50ulAnti-RNF4 Antibody
MBS9131957-01RNF4 Polyclonal Antibody
AMM22286G-01RNF4 Antibody [AMM22286G]
378613RNF4

Popular Products