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CNGA3 Antibody

CAT: 0247-OACA08007-50ULSize: 50 µLDry Ice: NoHazardous: No
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CAT#:0247-OACA08007-50ULSize:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Cyclic nucleotide gated channel subunit alpha 3
Gene Aliases
ACHM2; CCNC1; CCNCa; CCNCalpha; CNCG3; CNG channel alpha-3; CNG3; CNG-3; cone photoreceptor cGMP-gated channel alpha subunit; cone photoreceptor cGMP-gated channel subunit alpha; cyclic nucleotide gated channel alpha 3; cyclic nucleotide-gated cation channel alpha-3; Cyclic nucleotide-gated channel alpha-3.
Gene ID
1261
Accession Number
NP_001073347
Reactivity
Human
Immunogen
Recombinant Human Cyclic nucleotide-gated cation channel alpha-3 protein (1-165AA)
Target
Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cyclic GMP which leads to an opening of the cation channel and thereby causing a depolarization of cone photoreceptors. Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficacy of the channel when coexpressed with CNGB3 (By similarity) . Essential for the generation of light-evoked electrical responses in the red-, green- and blue sensitive cones.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunohistochemistry
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
-20°C or -80°C
Fragment
IgG
NCBI Gene Symbol
CNGA3
Host or Source
Rabbit
Protein Name
Cyclic nucleotide-gated cation channel alpha-3
Gene Name URL
CNGA3
Nucleotide Accession Number
NM_001079878

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