PPM1D Antibody

CAT: 0247-OACA07882-50ULSize: 50 µLDry Ice: NoHazardous: No
CAT#:0247-OACA07882-50ULSize:50 µL
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CAS Number
9007-83-4
Gene Name
Protein phosphatase, Mg2+/Mn2+ dependent 1D
Gene Aliases
IDDGIP; JDVS; p53-induced protein phosphatase 1; PP2C-DELTA; protein phosphatase 1D; Protein phosphatase 2C isoform delta; Protein phosphatase magnesium-dependent 1 delta; protein phosphatase Wip1; wild-type p53-induced phosphatase 1; WIP1.
Gene ID
8493
Accession Number
NP_003611
Reactivity
Human|Rat
Immunogen
Recombinant Human Protein phosphatase 1D protein (1-250AA)
Target
Involved in the negative regulation of p53 expression (PubMed:23242139) . Required for the relief of p53-dependent checkpoint mediated cell cycle arrest. Binds to and dephosphorylates 'Ser-15' of TP53 and 'Ser-345' of CHEK1 which contributes to the functional inactivation of these proteins (PubMed:15870257, PubMed:16311512) . Mediates MAPK14 dephosphorylation and inactivation (PubMed:21283629) . Is also an important regulator of global heterochromatin silencing and critical in maintaining genome integrity (By similarity) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunohistochemistry|Western blot
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
-20°C or -80°C
Fragment
IgG
NCBI Gene Symbol
PPM1D
Host or Source
Rabbit
Protein Name
Protein phosphatase 1D
Gene Name URL
PPM1D
Nucleotide Accession Number
NM_003620

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