PPM1D Antibody

• Gene Name:

  Protein phosphatase, Mg2+/Mn2+ dependent 1D

• Gene Aliases:

  IDDGIP; JDVS; p53-induced protein phosphatase 1; PP2C-DELTA; protein phosphatase 1D; Protein phosphatase 2C isoform delta; Protein phosphatase magnesium-dependent 1 delta; protein phosphatase Wip1; wild-type p53-induced phosphatase 1; WIP1.

• Gene ID:

  8493

• Accession Number:

  NP_003611

• Reactivity:

  Human|Rat

• Immunogen:

  Recombinant Human Protein phosphatase 1D protein (1-250AA)

• Target:

  Involved in the negative regulation of p53 expression (PubMed:23242139) . Required for the relief of p53-dependent checkpoint mediated cell cycle arrest. Binds to and dephosphorylates 'Ser-15' of TP53 and 'Ser-345' of CHEK1 which contributes to the functional inactivation of these proteins (PubMed:15870257, PubMed:16311512) . Mediates MAPK14 dephosphorylation and inactivation (PubMed:21283629) . Is also an important regulator of global heterochromatin silencing and critical in maintaining genome integrity (By similarity) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  Enzyme-linked immunosorbent assay|Immunohistochemistry|Western blot

• Purification:

  Affinity Purified

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Format:

  Liquid

• Reconstitution:

  -20°C or -80°C

• Fragment:

  IgG

• NCBI Gene Symbol:

  PPM1D

• Host or Source:

  Rabbit

• Protein Name:

  Protein phosphatase 1D

• Gene Name URL:

  PPM1D

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_003620