Products for Research Use Only
RegisterLogin

TSEN2 Antibody

CAT: 0247-OACA07692-100ULSize: 100 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0247-OACA07692-100ULSize:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
9007-83-4
Gene Name
TRNA splicing endonuclease subunit 2
Gene Aliases
HsSen2; PCH2B; SEN2; SEN2L; tRNA-intron endonuclease Sen2; tRNA-splicing endonuclease subunit Sen2; TSEN2 tRNA splicing endonuclease subunit.
Gene ID
80746
Accession Number
NP_001138864
Reactivity
Human
Immunogen
Recombinant Human tRNA-splicing endonuclease subunit Sen2 protein (1-220AA)
Target
Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body. Isoform 1 probably carries the active site for 5'-splice site cleavage. The tRNA splicing endonuclease is also involved in mRNA processing via its association with pre-mRNA 3'-end processing factors, establishing a link between pre-tRNA splicing and pre-mRNA 3'-end formation, suggesting that the endonuclease subunits function in multiple RNA-processing events. Isoform 2 is responsible for processing a yet unknown RNA substrate. The complex containing isoform 2 is not able to cleave pre-tRNAs properly, although it retains endonucleolytic activity.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunohistochemistry|Western blot
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
-20°C or -80°C
Fragment
IgG
NCBI Gene Symbol
TSEN2
Host or Source
Rabbit
Protein Name
TRNA-splicing endonuclease subunit Sen2
Gene Name URL
TSEN2
Nucleotide Accession Number
NM_001145392

Related Products

CatalogName
OCOA19425-20UGTSEN2 Protein Lysate
OCOA19424-20UGTSEN2 Protein Lysate
OCOA07995-20UGTSEN2 Protein Lysate
OCOA19423-20UGTSEN2 Protein Lysate
AAP83032-100UGTSEN2 Peptide - middle region (AAP83032)
AAP62409-100UGTSEN2 Peptide - C-terminal region (AAP62409)
OAMA00822-1MGWAS Antibody
OAMA00821-1MGWAS Antibody
OACD01074-100ULWAS Antibody
OASG07565-100ULWAS Antibody

Alternative Products

CatalogName
GWB-MW580DTSEN2 Antibody

Popular Products