NAA10 Antibody

9007-83-4

N-alpha-acetyltransferase 10, NatA catalytic subunit

ARD1; ARD1 homolog A, N-acetyltransferase; ARD1A; ARD1P; arrest defective protein 1; DXS707; hARD1; MCOPS1; N-acetyltransferase ARD1, human homolog of; N-alpha-acetyltransferase 10; natA catalytic subunit Naa10; NATD; N-terminal acetyltransferase complex ARD1 subunit homolog A; OGDNS; TE2.

8260

NP_001243048

Human

Recombinant Human N-alpha-acetyltransferase 10 protein (161-235AA)

Catalytic subunit of the N-terminal acetyltransferase A (NatA) complex which displays alpha (N-terminal) acetyltransferase activity (PubMed:15496142, PubMed:19826488, PubMed:19420222, PubMed:20145209, PubMed:27708256, PubMed:25489052) . Acetylates amino termini that are devoid of initiator methionine (PubMed:19420222) . The alpha (N-terminal) acetyltransferase activity may be important for vascular, hematopoietic and neuronal growth and development. Without NAA15, displays epsilon (internal) acetyltransferase activity towards HIF1A, thereby promoting its degradation (PubMed:12464182) . Represses MYLK kinase activity by acetylation, and thus represses tumor cell migration (PubMed:19826488) . Acetylates, and stabilizes TSC2, thereby repressing mTOR activity and suppressing cancer development (PubMed:20145209) . Acetylates HSPA1A and HSPA1B at 'Lys-77' which enhances its chaperone activity and leads to preferential binding to co-chaperone HOPX (PubMed:27708256) . Acts as a negative regulator of sister chromatid cohesion during mitosis (PubMed:27422821) .

Unconjugated

Polyclonal Antibody

Enzyme-linked immunosorbent assay|Immunohistochemistry|Western blot

Affinity Purified

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Liquid

-20°C or -80°C

IgG

NAA10

Rabbit

N-alpha-acetyltransferase 10

NAA10