Products for Research Use Only
RegisterLogin

HCK Antibody

CAT: 0247-OACA06614-100ULSize: 100 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0247-OACA06614-100ULSize:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
9007-83-4
Gene Name
HCK proto-oncogene, Src family tyrosine kinase
Gene Aliases
Hematopoietic cell kinase; hemopoietic cell kinase; JTK9; p59Hck; p59-HCK/p60-HCK; p61Hck; tyrosine-protein kinase HCK.
Gene ID
3055
Accession Number
NP_001165600
Reactivity
Human
Immunogen
Recombinant Human Tyrosine-protein kinase HCK protein (1-220AA)
Target
Non-receptor tyrosine-protein kinase found in hematopoietic cells that transmits signals from cell surface receptors and plays an important role in the regulation of innate immune responses, including neutrophil, monocyte, macrophage and mast cell functions, phagocytosis, cell survival and proliferation, cell adhesion and migration. Acts downstream of receptors that bind the Fc region of immunoglobulins, such as FCGR1A and FCGR2A, but also CSF3R, PLAUR, the receptors for IFNG, IL2, IL6 and IL8, and integrins, such as ITGB1 and ITGB2. During the phagocytic process, mediates mobilization of secretory lysosomes, degranulation, and activation of NADPH oxidase to bring about the respiratory burst. Plays a role in the release of inflammatory molecules. Promotes reorganization of the actin cytoskeleton and actin polymerization, formation of podosomes and cell protrusions. Inhibits TP73-mediated transcription activation and TP73-mediated apoptosis. Phosphorylates CBL in response to activation of immunoglobulin gamma Fc region receptors. Phosphorylates ADAM15, BCR, ELMO1, FCGR2A, GAB1, GAB2, RAPGEF1, STAT5B, TP73, VAV1 and WAS.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunohistochemistry
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
-20°C or -80°C
Fragment
IgG
NCBI Gene Symbol
HCK
Host or Source
Rabbit
Protein Name
Tyrosine-protein kinase HCK
Gene Name URL
HCK
Nucleotide Accession Number
NM_001172129

Related Products

CatalogName
OCOA21159-20UGHCK Protein Lysate
OCOA14284-20UGHCK Protein Lysate
OPCD03822-200UGHCK Recombinant Protein
OPCD03821-200UGHCK Recombinant Protein
OCOA21176-20UGHCK Protein Lysate
OPCD03821-10UGHCK Recombinant Protein
OPCD03821-50UGHCK Recombinant Protein
OPCD03822-50UGHCK Recombinant Protein
OPCD03822-10UGHCK Recombinant Protein
OKCD08171-96WHCK ELISA Kit (Human)

Alternative Products

CatalogName
MBS8529199-01H2B Antibody Antibody
MBS8513599-01CD11b Antibody Antibody
DF8746-01ASAP1 antibody Antibody
MBS850197-01Antibody to IGFBP2 Antibody
E36403ZNF98 Antibody Antibody
GWB-250026Lck antibody Antibody
E8M1007-4HSP60 Antibody Antibody
MBS9403836-01SZT2 Antibody Antibody
LSMab09882anti-Antibody^Polyclonal antibody control antibody
GWB-5C6547MAD1L1 antibody [9B10] Antibody

Popular Products